Regulation of IL-6 system in cerebrospinal fluid and serum compartments by seizures: the effect of seizure type and duration.

Experimental studies suggest that cytokine production may be triggered by seizure activity. Here we determined the levels of interleukin-6 (IL-6) and its soluble receptor components (sIL-6R and sGp130) in CSF and serum from control subjects and patients after different types of seizures…. These results provide further support for a hypothesis of cytokine production induced by seizure activity per se.

Abstract. Journal of neuroimmunology 2004; 152(1-2):121-5