The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring.
Viral infection during pregnancy has been correlated with increased frequency of autism spectrum disorder (ASD) in offspring…. Our data suggest that therapeutic targeting of TH17 cells in susceptible pregnant mothers may reduce the likelihood of bearing children with inflammation-induced ASD-like phenotypes.
Abstract. Science (New York, N.Y.) 2016; 351(6276):933-9