Neurotoxic effect of enteral aluminium

Long Evans rats were treated for 90 days with water-soluble, insoluble or chelated aluminium compounds…. Acetylcholinesterase activity increased and choline-acetyltransferase activity decreased, resulting in a diminished cholinergic activity, which is a characteristic of Alzheimer’s disease.

Abstract. Food and chemical toxicology: An International journal published for the British Industrial Biological Research Association 1993; 31(5):357-61