Metabolic consequences of interleukin 6 challenge in developing neurons and astroglia

Maternal immune activation and subsequent interleukin-6 (IL-6) induction disrupt normal brain development and predispose the offspring to developing autism and schizophrenia…. Our findings are potentially critical for understanding the mechanism by which IL-6 disrupts brain function, and they provide information about the molecular cascade that links maternal immune activation to developmental brain disorders.

Abstract. Journal of neuroinflammation 2014; 11():183