Microglial activation in young adults with autism spectrum disorder-1

This study seeks to identify brain regions associated with excessively activated microglia in the whole brain, and to examine similarities in the pattern of distribution of activated microglia in subjects with ASD and control subjects…. The results indicate excessive microglial activation in multiple brain regions in young adult subjects with ASD. The similar distribution pattern of regional microglial activity in the ASD and control groups may indicate augmented but not altered microglial activation in the brain in the subjects with ASD.

Abstract. JAMA Psychiatry. 2013 Jan;70(1):49-58. doi: 10.1001/jamapsychiatry.2013.272.