Latest Articles
Brain Development in Rodents and Humans: Identifying Benchmarks of Maturation and Vulnerability to Injury Across Species
Hypoxic-ischemic and traumatic brain injuries are leading causes of long-term mortality and disability in infants and children.... We consider the timing of neurogenesis, synaptogenesis, gliogenesis,...
Autism Spectrum Disorder Secondary to Enterovirus Encephalitis
We describe a 32-month-old patient with enteroviral encephalitis confirmed by polymerase chain reaction in cerebrospinal fluid, with unfavorable clinical course with marked developmental regression, autistic...
Austistic Symptoms Following Herpes Encephalitis
Autism is a childhood onset neurodevelopmental disorder characterized by reciprocal social deficits, communication impairment, and rigid ritualistic interests, with the onset almost always before three...
Onset at age 14 of a typical autistic syndrome A case report
Journal of autism and developmental disorders 1986; 16(3):369-75 No abstract available
Autistic disorder and viral infections
One proposed etiology for autism is viral infection very early in development.... Many studies over the years have presented evidence both for and against the...
Acquired reversible autistic syndrome in acute encephalopathic illness in children
In seeking the neurologic substrate of the autistic syndrome of childhood, previous studies have implicated the medial temporal lobe or the ring of mesolimbic cortex...
Early effects of lipopolysaccharide- induced inflammation on foetal brain development in rat
Studies in humans and animal models link maternal infection and imbalanced levels of inflammatory mediators in the foetal brain to the aetiology of neuropsychiatric disorders.......
Maternal immune activation by LPS selectively alters specific gene expression profiles
Maternal immune activation (MIA) is a risk factor for the development of schizophrenia and autism. Infections during pregnancy activate the mother's immune system and alter...
Regional differences in synaptogenesis in human cerebral cortex
The formation of synaptic contacts in human cerebral cortex was compared in two cortical regions: auditory cortex (Heschl's gyrus) and prefrontal cortex (middle frontal gyrus).......
Metabolic consequences of interleukin 6 challenge in developing neurons and astroglia
Maternal immune activation and subsequent interleukin-6 (IL-6) induction disrupt normal brain development and predispose the offspring to developing autism and schizophrenia.... Our findings are potentially...