Latest Articles
Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
Abnormal immune responses have been reported to be associated with autism. A number of studies showed that cytokines were increased in the blood, brain, and...
Gestational Exposure to a Viral Mimetic Poly(I-C) Results in Long-Lasting Changes in Mitochondrial Function by Leucocytes in the Adult Offspring
Maternal immune activation (MIA) is a potential risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ). The present study reports for the first time...
Maternal immune activation causes age and region-specific changes in brain cytokines in offspring throughout development.
Maternal infection is a risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ).... Data indicate that MIA leads to long-lasting, region-specific changes in brain...
Microglial activation in young adults with autism spectrum disorder-1
This study seeks to identify brain regions associated with excessively activated microglia in the whole brain, and to examine similarities in the pattern of distribution...
Pregnancy, Immunity, Schizophrenia, and Autism
(2006). Engineering and Science, 69(3), 10-21.
Elevated immune response in the brain of autistic patients.
This study determined immune activities in the brain of ASD patients and matched normal subjects by examining cytokines in the brain tissue.... ASD patients displayed...
Neuroglial Activation and Neuroinflammation in the Brain of Patients with Autism
Autism is a neurodevelopmental disorder characterized by impaired communication and social interaction and may be accompanied by mental retardation and epilepsy. Findings indicate that innate...
Gender-Dependent Effects of Maternal Immune Activation on the Behavior of Mouse Offspring
Autism spectrum disorders are neurodevelopmental disorders characterized by two core symptoms; impaired social interactions and communication, and ritualistic or repetitive behaviors. Findings indicate that offspring...
Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism
The core symptoms of autism are deficits in social interaction and language, and the presence of repetitive/stereotyped behaviors. The results indicate that MIA yields male...
Dissolving Illusions: Disease, Vaccines, and The Forgotten History
Not too long ago, lethal infections were feared in the Western world. Since that time, many countries have undergone a transformation from disease cesspools to...