Gadad Administration of thimerosal containing vaccines to infant rhesus macaques does not result in autism like behavior or neuropathology
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder…. These data indicate that administration of TCVs and/or the MMR vaccine to rhesus macaques does not result in neuropathological abnormalities, or aberrant behaviors, like those observed in ASD. Abstract. Proceedings of the National Academy of Sciences of the United States of America 2015; 112(40):12498-503
Read MoreMortality reduction with influenza vaccine in patients with pneumonia outside “flu” season: pleiotropic benefits or residual confounding?
Objectives: To evaluate unrecognized confounding by hypothesizing the presence of a 50% mortality reduction with vaccination for patients with pneumonia outside of influenza season…. Conclusions: The 51% reduction in mortality with vaccination initially observed in patients with pneumonia who did not have influenza was most likely a result of confounding. Previous observational studies may have…
Read MoreAdverse Events following 12 and 18 Month Vaccinations: a Population-Based, Self-Controlled Case Series Analysis
Live vaccines have distinct safety profiles, potentially causing systemic reactions one to 2 weeks after administration…. There are significantly elevated risks of primarily emergency room visits approximately one to two weeks following 12 and 18 month vaccination. Future studies should examine whether these events could be predicted or prevented. Abstract. PloS one 2011; 6(12):e27897
Read MoreConfounding in studies of adverse reactions to vaccines.
Several social and medical attributes are associated with both avoidance or delay of vaccination and an increased risk of adverse events such as sudden infant death syndrome or childhood encephalopathy…. This paper reviews the literature on studies of severe adverse events after the administration of pertussis antigen-containing vaccines, with particular attention to the measures taken…
Read MoreVaccines are not associated with autism An evidence-based meta-analysis of case-control and cohort studies
There has been enormous debate regarding the possibility of a link between childhood vaccinations and the subsequent development of autism…. The cohort data revealed no relationship between vaccination and autism (OR: 0.99; 95% CI: 0.92 to 1.06) or ASD (OR: 0.91; 95% CI: 0.68 to 1.20), nor was there a relationship between autism and MMR…
Read MoreWhat is the role of vitamin D in autism?
A growing body of literature suggests that higher serum 25-hydroxyvitamin D [25(OH)D] concentrations, either in utero or in early life, may reduce the risk of autism…. Because activated vitamin D, a secosteroid, upregulates DNA-repair genes, vitamin D deficiency during development may inhibit the repair of de novo DNA mutations in fetuses and infants and thus…
Read MoreVitamin D for Those with Neurodevelopmental Disorders and Intellectual Disabilities
The Vitamin D Task Force of the American Academy of Developmental Medicine and Dentistry (AADMD) reviewed the evidence of 25(OH)D concentrations that benefit the health of persons with developmental disabilities. Maintaining recommended optimal serum 25(OH)D concentrations year long will benefit skeletal development in infants, children, and adolescents, and benefit musculoskeletal health and neuromuscular coordination in…
Read MoreAutism occurrence by MMR vaccine status among US children with older siblings with and without autism.
Abstract. JAMA 2015; 313(15):1534-40
Read MoreOn-time Vaccine Receipt in the First Year Does Not Adversely Affect Neuropsychological Outcomes
To determine whether children who received recommended vaccines on time during the first year of life had different neuropsychological outcomes at 7 to 10 years of age as compared with children with delayed receipt or nonreceipt of these vaccines…. Timely vaccination during infancy has no adverse effect on neuropsychological outcomes 7 to 10 years later.…
Read MoreA Population-based Study Of Measles, Mumps, And Rubella Vaccination And Autism
It has been suggested that vaccination against measles, mumps, and rubella (MMR) is a cause of autism…. There was no association between the age at the time of vaccination, the time since vaccination, or the date of vaccination and the development of autistic disorder. This study provides strong evidence against the hypothesis that MMR vaccination…
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