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Maternal immune activation causes age and region-specific changes in brain cytokines in offspring throughout development.
Maternal infection is a risk factor for autism spectrum disorder (ASD) and schizophrenia (SZ).... Data indicate that MIA leads to long-lasting, region-specific changes in brain...
Microglial activation in young adults with autism spectrum disorder-1
This study seeks to identify brain regions associated with excessively activated microglia in the whole brain, and to examine similarities in the pattern of distribution...
Pregnancy, Immunity, Schizophrenia, and Autism
(2006). Engineering and Science, 69(3), 10-21.
Elevated immune response in the brain of autistic patients.
This study determined immune activities in the brain of ASD patients and matched normal subjects by examining cytokines in the brain tissue.... ASD patients displayed...
Neuroglial Activation and Neuroinflammation in the Brain of Patients with Autism
Autism is a neurodevelopmental disorder characterized by impaired communication and social interaction and may be accompanied by mental retardation and epilepsy. Findings indicate that innate...
Gender-Dependent Effects of Maternal Immune Activation on the Behavior of Mouse Offspring
Autism spectrum disorders are neurodevelopmental disorders characterized by two core symptoms; impaired social interactions and communication, and ritualistic or repetitive behaviors. Findings indicate that offspring...
Maternal immune activation yields offspring displaying mouse versions of the three core symptoms of autism
The core symptoms of autism are deficits in social interaction and language, and the presence of repetitive/stereotyped behaviors. The results indicate that MIA yields male...
Aluminum Adjuvant Linked to Gulf War Illness Induces Motor Neuron Death in Mice
Gulf War Illness (GWI) affects a significant percentage of veterans of the 1991 conflict, but itsorigin remains unknown. Associated with some cases of GWI are...
Measles, Mumps, and Rubella Vaccination and Autism NEJM letters
On October 24, 2002, an article about septal ablation with alcohol for hypertroph-ic cardiomyopathy was published in the Journal.