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Neurotoxic effects of postnatal thimerosal are mouse strain dependent
The developing brain is uniquely susceptible to the neurotoxic hazard posed by mercurials. Host differences in maturation, metabolism, nutrition, sex, and autoimmunity influence outcomes. ...Autoimmune...
An investigation of porphyrinuria in Australian children with autism
Two recent studies, from France (Nataf et al., 2006) and the United States (Geier & Geier, 2007), identified atypical urinary porphyrin profiles in children with...
A Prospective Blinded Evaluation of Urinary Porphyrins Verses the Clinical Severity of Autism Spectrum Disorders
A prospective, blinded study evaluated the relationship between autism spectrum disorder (ASD) severity measured by Childhood Autism Rating Scale (CARS) scores and urinary porphyrins among...
Addressing Parents’ Concerns: Do Vaccines Contain Harmful Preservatives, Adjuvants, Additives, or Residuals?
Vaccines often contain preservatives, adjuvants, additives, or manufacturing residuals in addition to pathogen-specific immunogens. ...Quantities of mercury, aluminum, formaldehyde, human serum albumin, antibiotics, and yeast...
A Dose-Response Relationship between Organic Mercury Exposure from Thimerosal-Containing Vaccines and Neurodevelopmental Disorders
A hypothesis testing case-control study evaluated concerns about the toxic effects of organic-mercury (Hg) exposure from thimerosal-containing (49.55% Hg by weight) vaccines on the risk...
A Prospective Study of Mercury Toxicity Biomarkers in Autistic Spectrum Disorders 2007
Porphyrins are derivatives formed in the heme synthesis pathway and porphyrins afford a measure of xenobiotic exposure.... Mercury toxicity was associated with elevations in urinary...
Aluminium-induced electrophysiological, biochemical and cognitive modifications in the hippocampus of aging rats.
Aluminium (Al) is the most abundant metal known for its neurotoxicity in humans.... It has been reported to be involved in the etiology of several...
Aluminum chloride induces neuroinflammation, loss of neuronal dendritic spine and cognition impairment in developing rat.
Aluminum (Al) is present in the daily life of humans, and the incidence of Al contamination increased in recent years. Long-term excessive Al intake induces...
Neurotoxic effect of enteral aluminium
Long Evans rats were treated for 90 days with water-soluble, insoluble or chelated aluminium compounds.... Acetylcholinesterase activity increased and choline-acetyltransferase activity decreased, resulting in a...
Curcumin attenuates aluminium-induced functional neurotoxicity in rats
Curcumin is a polyphenol extracted from the rhizome of Curcuma longa and well known as a multi-functional drug with antioxidative, anti-cancerous and anti-inflammatory activities.... Our...