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On-time Vaccine Receipt in the First Year Does Not Adversely Affect Neuropsychological Outcomes
To determine whether children who received recommended vaccines on time during the first year of life had different neuropsychological outcomes at 7 to 10 years...
A Population-based Study Of Measles, Mumps, And Rubella Vaccination And Autism
It has been suggested that vaccination against measles, mumps, and rubella (MMR) is a cause of autism.... There was no association between the age at...
Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction
Dysregulated cytokine expression and signaling are major contributors to a number of autoimmune diseases.... Because this mechanism also enhanced experimental autoimmune encephalomyelitis (EAE) in wild-type...
Increased production of IL-17 in children with autism spectrum disorders and co-morbid asthma
Inflammation and asthma have both been reported in some children with autism spectrum disorder (ASD).... In conclusion, children with ASD exhibited a differential response to...
Elevated serum levels of interleukin-17A in children with autism
The T-helper (Th)1/Th2 dichotomy dominated the field of immune regulation until interleukin (IL)-17-expressing T cells (Th17) were proposed to be a third lineage of helper...
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring.
Viral infection during pregnancy has been correlated with increased frequency of autism spectrum disorder (ASD) in offspring.... Our data suggest that therapeutic targeting of TH17...
Regulation of IL-6 system in cerebrospinal fluid and serum compartments by seizures: the effect of seizure type and duration.
Experimental studies suggest that cytokine production may be triggered by seizure activity. Here we determined the levels of interleukin-6 (IL-6) and its soluble receptor components...
Interleukin-6 and interleukin-1 receptor antagonist in cerebrospinal fluid from patients with recent tonic-clonic seizures.
We have previously reported increased concentrations of interleukin (1L)-6 in CSF from patients with tonic-clonic seizures, where increased cytokine production most likely is a consequence...
Cerebral microglia recruit monocytes into the brain in response to tumor necrosis factoralpha signaling during peripheral organ inflammation.
In inflammatory diseases occurring outside the CNS, communication between the periphery and the brain via humoral and/or neural routes results in central neural changes and...
Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-?B and STAT3 Signaling.
Current therapeutic approaches of Alzheimer's disease (AD) are symptomatic and of modest efficacy, and there is no available effective cure or prevention of AD; hence,...